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diagnosis sle druginduced erythematosus hematology syndrome systemic activation approach blood comparison cppd deposition dermatology differential dil joint laboratory macrophage mas
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... • Immunologic Workup ... Evolution: Chronic disease ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Initial screening test ... #diagnosis #rheumatology ... #management
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... categories of joint disease ... dihydrate • Basic calcium ... Joint #Pain #MSK #rheumatology ... #approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... crystals (gout) or calcium ... joint • Systemic lupus ... profile (e.g., calcium ... #laboratory #workup
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... • Immunologic Workup ... Evolution: Chronic disease ... comparison #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... SJIA], systemic lupus ... Liver function tests ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary ... - Calcium Pyrophosphate ... precipitates with calcium ... #Rheumatology # ... diagnosis #management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... • Immunologic Workup ... #DIL #rheumatology ... diagnosis #treatment #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... nonerosive inflammatory arthritis ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusions One Pager Summary ... indirect Coombs test ... binds to serum calcium ... Transfusions #diagnosis #management ... #hematology #reactions
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