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diagnosis hematology algorithm dermatology management classification generalized oncology pathophysiology pruritus systemic acidosis acromegaly activation agglutinin arteritis cold disease elevatedmcv elevation
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... effect following treatment ... Iron deficiency anemia ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Myelodysplastic Syndromes ... Liver Function Tests ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... #rheumatology #
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts ... • These shifts ... hyperparathyroidism • Secondary ... hyperparathyroidism Treatment ... #Nutrition #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts ... plasma insulin (treatment ... hyperaldosteronism, Secondary ... megaloblastic anemia ... #differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... DDX: Rule Out Secondary ... Causes • Anemia ... blood count with differential ... #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... result in severe anemia ... immune hemolytic anemia ... WBC count and differential ... leukocytosis with a left shift
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