27 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... (GI symptoms/endemic ... changes), high MCV anemia ... #Causes #Workup
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Differential #Diagnosis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... #Effusions #causes ... #differential #diagnosis ... #msk #physicalexam
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
elevation • Nausea ... 14%), in which case ... enzymes ↑ • Mild anemia ... Viral hepatitis Diagnosis ... #HIV #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... Aseptic necrosis of hip ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... test #cold # ... #hematology #diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
hydrocephalus, HIV ... ... laboratory tests ... Alzheimer - 1st cause ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... result in severe anemia ... immune hemolytic anemia ... leukocytosis with a left shift ... #Workup #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - HCV - HIV ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management