16 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
) Three syndromes ... Elevated Liver tests ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... source - Tests ... function may be abnormal ... • Gilbert's syndrome
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... Areas of diagnostic ... ALP, alkaline phosphatase ... #Algorithm #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... • Gilbert's syndrome ... liver #chemistry #diagnosis ... #differential #Hepatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Elevated Liver tests ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... obstruction • ALP ... Differential Diagnosis ... : • Viral hepatitis ... #workup #hepatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Positive pathergy test ... is a skin prick test ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia: - Hepatitis ... (MDS) (normal or ... Anemia #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases and hepatitis ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management