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diagnosis differential workup oncology pancytopenia chronic cll elevatedmcv hyperkalemia intercellularshift leukemia lymphocytic macrocytic macrocytosis management mds myelodysplasia myelodysplastic syndromes thromboticthrombocytopenicpurpura
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... : • Peripheral ... may result from low
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... #Causes #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Sequestration Peripheral ... Production - Flow ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Sequestration Peripheral ... Production - Flow ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
, tests to detect ... result in severe anemia ... the range of Peripheral ... leukocytosis with a left shift ... Diagnosis #Workup #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Out Secondary Causes ... • Anemia • Aplastic ... #diagnosis #hematology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... , TTKG, distal flow ... Non-Anion Gap Metabolic ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... cytometry • Peripheral ... • Neutropenia, anemia ... Pure red cell aplasia ... workup #oncology #hematology
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