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diagnosis differential rheumatology dermatology erythematosus systemic vasculitis arthropathies arthropathy autoimmune causes classification complications ddxof disorders joint maculopapular manifestations monoarthritis monoarticular
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve ... erythematosus #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Ill-appearing, vital sign ... sulfa-drug - Skin ... #Dermatology #Rash ... Maculopapular #Scaling #Color ... #Differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... permanent alopecia Differential ... Seizures • Strokes Skin ... : • Symptoms limited
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... soles • Discoid Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... commonly affects the skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... ) • Anti-Mi2 (skin ... : • Gottron rash ... papules and Gottron sign ... ) • Shawl sign
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