92 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
the Mnemonic "no skin ... dermatology-mnemonics-6011359#5 #diagnosis ... #differential # ... symptoms #signs ... #dermatology #skin
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
LcSSc) - distal skin ... DcSSc; diffuse) - skin ... changes): skin ... #signs #symptoms ... #testing #workup
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... , the differential ... Kawasaki disease ... #Differential
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation ... pain/swelling - Fever
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... organ-specific signs ... , skin or esophageal ... #Differential # ... diagnosis #hematology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Clinical: • Disease ... Constitutional: Fever ... neuropathies • Skin ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Causes == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... #Diagnosis #Algorithm
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... • Rheumatic fever ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... - Vasculitic skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
trigger - Direct skin ... and duration of symptoms ... 50% of patients Skin ... - Headache, fever ... 1% of patients Skin