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diagnosis dermatology differential management signs symptoms syndrome classification erythematosus lupus sle systemic antimda5 antimda5dm autoimmune behcet cryofibrinogenemia cryoglobulinemia cryoglobulins dermatologic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... - Skin, glomeruli ... glomerular ischemia - Skin ... Small Vessels: Skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... : • Skin lesions
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... GPA causes disease ... Skin lesions ... also occur Skin ... 16%) • Painful skin
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... erythematosus #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... #symptoms #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... reticularis & skin ... classification #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ulcerations • Skin ... ulcerations • Auricular skin ... auricular papules Clinical ... • Arthralgia/arthritis ... • Skin vasculopathies
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... required due to skip ... them, but urgent rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Vascular reactivity (Skin ... malignancies, vasculitis ... Painful ulcers • Skin ... to medium-sized arteries ... Warfarin-induced skin
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