38 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... of germinative skin ... Causes: 1) Exfoliative ... Basophils/Histamine 4) Skin-homing ... Nikolsky #Algorithm #Differential
Differentiating Features Between Central and Peripheral Cyanosis

Mechanism - Arterial destauration
Sites - Skin, mucous membrane of oral
destauration Sites - Skin ... therapy - Pulmonary cause ... Sites - Only skin ... Central #Peripheral #Comparison ... #Signs #Symptoms
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... trigger - Direct skin ... 50% of patients Skin ... 1% of patients Skin ... #rheumatology #comparison
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs/symptoms ... hypovolemia (dry MM, skin
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... 2) Presence of symptoms ... (HA, nausea, confusion ... status (edema, JVD, skin ... Pseudohyponatremia #Differential
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... Inflammation of skin ... granulomas under skin ... inflammation tends to cause ... #signs #symptoms
Pitting Edema on Physical Exam

Edema occurs when fluid that accumulates in tissues leads to swelling. When
a pit, in the skin ... non-pitting edema, the skin ... Symptoms may include ... skin which feels ... -Causes may include
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... eosinophilia (common causes ... (eg, skin or esophageal ... Disorders #Algorithm #Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Symptoms: • The ... Edema in 70% of cases ... Skin involvement ... Resolution > 15 days Differentials