16 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Arthralgia/arthritis, Skin ... fraction < 20% Differential ... diagnosis #management #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... injury) • Neurologic ... retinal damage) • Skin ... test (this is a skin ... ) Differential Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... commonly affects the skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... think about three clinical ... disease affecting ... Redundant eyelid skin ... #Differential #
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Pulmonary • Skin ... • M genavense Skin ... , adenitis, skin ... • M fortuitum Skin ... NTM #Infections #differential
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
has five major clinical ... osteomyelitis or skin ... organism into the skin ... Mouth, throat, skin ... ) #Mycoses #InfectiousDiseases
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... goiter (Graves' disease ... TRAb) if Graves' disease ... Thickening of skin ... causes #diagnosis #differential
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... neurosyphilis, cranial nerve ... have positive serology ... granuIomas on skin ... of Infectious Diseases
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... salivary ducts Clinical ... myelopathy, cranial nerve ... amyloidosis, PAH Skin ... : • Dry skin (xerosis
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
compression of nerve ... constipation Differential ... stimulation of skin ... axial T1 and T2 Treatment ... diagnosis #causes #neurology