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differential management symptoms hematology syndrome causes disease infections oncology vasculitis adultonset aids algorithm antinxp2 antinxp2dm arteritis autoimmune behcet cauda caudaequina
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Diaqnoses: • ... #management #treatment ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... glomerular ischemia - Skin ... Small Vessels: Skin ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Arthritis, AS Treatment ... #management #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin ... #Diagnosis #Rheumatology
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
↑ AST/ALT • Treatment ... Thickening of skin ... tenderness Treatment ... #differential # ... endocrinology #signs
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... osteomyelitis or skin ... organism into the skin ... Mouth, throat, skin ... ) #Mycoses #InfectiousDiseases
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... required due to skip ... Treatment of GCA ... them, but urgent rheumatology
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