20 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #management #treatment
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Purpura Fulminans Skin ... splenectomy 1d chills ... BIDMC Infectious Diseases ... Purpura #Fulminans #Skin ... #photo
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... weeks - Typical skin ... rash: maculopapular ... non-pruritic, salmon-pink rash ... #AdultOnset #Stills
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Skin Rash 40 ... colonize human skin ... University Infectious Diseases ... #Canimorsus #Skin ... #clinical #photo
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... usually to TEN in adults ... staphylococcal scalded skin ... includes Kawasaki disease ... erythematous rash
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... onset of fever, chills ... chronic liver disease ... Vibrio #Vulnificus #skin ... legs #clinical #photo
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... anti-lL6R, anti-ILI #Adult ... #onset #Stills ... #rheumatology #management
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... biopsy preferred Differential ... University Infectious Diseases ... Infection #clinical #photo
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Skin involvement ... Resolution > 15 days Differentials ... withdrawal • Mild disease