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diagnosis differential rheumatology dermatology algorithm pain skin causes disorders erythematosus joint lupus msk signs sle stages symptoms syphilis systemic treatment
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... • Shin splints ... Brittle nails - Skin ... skin • Inflammation
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #rashes #differential
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... syndrome (SSS) ... includes Kawasaki disease ... erythematous rash
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... vasculitis Skin ... also occur Skin ... 16%) • Painful skin ... Skin Biopsy
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #diagnosis #management
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
of hair, eyes, skin ... sclerosis (white "ash ... • Addison's disease ... McCune Albright syndrome ... Hyperpigmentation #disorders #skin
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... like “butterfly rash ... Disorders #msk #Differential
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... to inflammatory skin ... Generalized itchy rash ... osteitis) - Pustular skin ... #Pustular #Skin
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Skin involvement ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome
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