14 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
with more severe disease ... activity Anti-Ro ... Associated with skin ... Treatment: • ... #rheumatology #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Skin involvement ... Resolution > 15 days Differentials ... : symptomatic treatment ... • Severe disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... ) Differential Diagnosis ... Arthritis, AS Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Tuberculin skin ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Tuberculin skin ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
irreversible muscle and nerve ... over the involved skin ... area of erythema, skin ... function and reflex activity ... #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... myelopathy, cranial nerve ... amyloidosis, PAH Skin ... : • Dry skin (xerosis ... Adenocarcinoma Treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
maculopapular skin ... activity! ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... conditions listed in differential ... diagnosis column Treatment ... between nerve cells ... neurology #diagnosis #management