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diagnosis differential rheumatology symptoms behcet blood causes classification conditions erythematosus extrarticular hematology hematuria joint lupus monoclonal myelitis nephrology ocular oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... - Skin, glomeruli ... glomerular ischemia - Skin ... Small Vessels: Skin
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... injury) • Neurologic ... retinal damage) • Skin ... test (this is a skin ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... : • Skin lesions
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... Hematology #Monoclonal #Differential
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria - Differential ... nephropathy - Thin ... hematuria • Signs ... Diagnostic of GN or vasculitis ... of glomerular disease
Ptosis - Differential Diagnosis Framework Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... disease affecting ... eyelid: • Third nerve ... Redundant eyelid skin ... #Differential #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... - SLE Neurologic ... , Vasculitis (e.g ... Scleroderma Thickened skin ... #joint #pain #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... myelopathy, cranial nerve ... amyloidosis, PAH Skin ... : • Dry skin (xerosis ... Rheumatology #Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... brain and/or optic nerve ... - Sjogren - Vasculitis ... Myelitis #diagnosis #management ... #neurology #differential
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