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diagnosis differential symptoms clinical dermatology disease syndrome vasculitis adultonset algorithm antinxp2 antinxp2dm arteritis autoimmune behcet blanching classification dermatomyositis disorders eosinophil
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Infection #clinical #photo
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Disease #diagnosis #management ... #treatment #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... commonly affects the skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin
Scleroderma Associated Telangiectasia. If you see them-round, often well circumscribed (but can be matte-like too) &
& blanchable, differential ... Telangiectasia #clinical #video ... #blanching #skin ... #dermatology #rheumatology
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 Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... required due to skip ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... myelopathy, cranial nerve ... amyloidosis, PAH Skin ... : • Dry skin (xerosis ... #Diagnosis #Management
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