23 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders ... - Differential Diagnosis ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... #msk #Differential
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Purpura - Skin ... reticularis & skin ... (e.g. systemic ... classification #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
) is a skin condition ... inflamed or blistered skin ... Rare Disorder: ... development of skin ... deeper into the skin
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... organ-specific signs ... symptoms (eg, skin ... #Algorithm #Differential ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #rheumatology #
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
trauma leads to skin ... , painless, no systemic ... signs, labs normal ... biopsy preferred Differential ... Infection #clinical #photo
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... central nervous system ... Peripheral Nervous System ... Lack of UMN/LMN signs
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin ... , Loose anagen syndrome ... Examination: • Signs ... Examine the entire skin ... Vitamin D levels Systemic