12 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... symptoms (eg, skin ... #Disorders #Algorithm ... #Differential # ... diagnosis #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #diagnosis #rheumatology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
of germinative skin ... Exfoliative toxin 2) Eosinophils ... Basophils/Histamine 4) Skin-homing ... #Diagnosis #Dermatology ... #Differential #
Scleroderma Associated Telangiectasia. 

If you see them-round, often well circumscribed (but can be matte-like too) &
& blanchable, differential ... Telangiectasia #clinical #video ... #blanching #skin ... #dermatology #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... glomerular ischemia - Skin ... Small Vessels: Skin ... #diagnosis #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... amyloidosis, PAH Skin ... : • Dry skin (xerosis ... phenomenon (16%) MSK ... Sjogrens #Syndrome #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... - Hepatitis, eosinophilic ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Scleroderma Thickened skin ... Amyloidosis • Eosinophilic ... #joint #pain #differential ... #diagnosis #rheumatology