15 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... commonly affects the skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
compression of nerve ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... stimulation of skin ... #differential #
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... Back pain • Skin ... changes • Urinary symptoms ... Abdominal cutaneous nerve ... Chronic #Causes #Differential
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Complications of DMARDs • Skin ... Thrombocytosis, Felty's syndrome ... #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Pulmonary • Skin ... • M genavense Skin ... disease, adenitis, skin ... • M fortuitum Skin ... NTM #Infections #differential