10 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Hyperpigmentation Differentials ... the Mnemonic "no skin ... #symptoms #signs ... #dermatology #skin ... #skinrash
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... >2 of: • skin ... Signs / Symptoms ... / Complications ... #Anaphylaxis #pathophysiology
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
hands & feet Signs ... /Symptoms/Complications ... - Generalized Skin ... Criteria #Diagnosis #Pathophysiology ... #Signs #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... diagnosis #management #signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
blisters on the skin ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... Pale and sweaty skin
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... Examination: • Skin ... bile ducts Differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
and ophthalmic complications ... systemic sx + signs ... very remarkable w/differential ... required due to skip ... required +/- prompt ophthalmology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
PRESENTATIONS - Dry skin ... (yellowing of skin ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry