24 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... neuropathies • Skin ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Symptoms: • The ... Skin involvement ... Resolution > 15 days Differentials
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Sporotrichiosis #Infection #clinical
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... The signs and symptoms ... ▪ “Rash” (75% ... #Diagnosis #Clinical
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease: Clinical ... • Polymorphous rash ... hands & feet Signs ... - Generalized Skin ... Rash #Kawasaki
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... #signs #symptoms
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... Disease #diagnosis #management
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Itching, Minor rash ... mucosal involvement, skin ... eosinophilia systemic symptoms ... there is a strong clinical ... Prescription #algorithm #management
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis