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diagnosis differential rheumatology dermatology syndrome clinical lupus management vasculitis acute aids autoimmune behcet canimorsus capnocytophaga classification compared comparison complications disease
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation on skin ... pathophysiology #diagnosis #signs ... #symptoms #complications
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Capnocytophaga Canimorsus Skin ... with wife, bit by his ... colonize human skin ... Capnocytophaga #Canimorsus #Skin ... #clinical #photo
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... Diagnosis #Clinical #Photo
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
sweats (28%) • Skin ... rash (48%) • ... elevation • Nausea ... 14%), in which case ... • New onset SLE
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... gyratum repens • A skin ... induratum • A chronic skin ... Erythemas #comparison #table ... #differential #
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Symptoms: • The ... Skin involvement ... Resolution > 15 days Differentials
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... Behcet disease) Differential ... diagnosis #management #signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... Pale and sweaty skin ... #diagnosis #causes
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