23 results
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors and Inotropes ... Increase SVR > Inotropy ... #criticalcare # ... pharmacology #comparison ... #shock #management
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... Bradyarrhythmias, Some cases ... #Vasopressors #Inotropes ... #comparison #table ... #pharmacology #criticalcare
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors and Inotropes ... pressor added in shock ... #Vasopressors #Inotropes ... #management #criticalcare ... #summary #comparison
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
and Management ... Vasopressors, Inotropes ... #Diagnosis #Management ... #Summary #criticalcare ... #treatment #workup
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Abdominal compartment syndrome ... Treatment Goals ... Differential #Diagnosis #criticalcare ... #algorithm #treatment ... #management
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
play a role in treatment ... pericarditis (select cases ... Refractory septic shock ... Indications #infections #management ... #treatment
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... findings based on cause ... anaphylaxis, release syndrome ... Diagnosis #table #comparison ... #criticalcare
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
Syndrome (STSS) ... GAS in 30% of cases ... necrosis STSS Treatment ... #Syndrome #STSS ... #treatment #management