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diagnosis rheumatology lupus erythematosus systemic cardiology cardiomyopathy comparison dil drugs hemophagocytic hlh indications infections lymphohistiocytosis peripartum pharmacology rhabdomyolysis risk steroids
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Summary • Epidemiology ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
Summary of Infections in which Steroids play a role in treatment • TB meningitis • TB
Summary of Infections ... play a role in treatment ... pericarditis (select cases ... infection per se ... #infections #management
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Summary Trauma ... #Summary #causes ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
with drug-induced SLE ... for 1 year of treatment ... Lupusreference #DrugInduced ... Erythematosus #medications ... pharmacology #risk #differential
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... Differential Diagnosis ... orthopnea, PND, LE ... #cardiology #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... Discontinuation of causal ... Lupusreference #DrugInduced ... #diagnosis #treatment ... #management
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