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Major Chemotherapy Toxicities - AntiNEOPlastic Man Mnemonic

Common Toxicities with Traditional Chemotherapeutic Medications 

Originally posted on pharmacologyweekly
Chemotherapeutic Medications ... #Chemotherapy #Toxicity ... #Toxicities #SideEffects
High yield pharmacology notes
#pharmacology #antibiotics #nephrology #sideeffects #syndrome #medications
#antibiotics #nephrology ... #sideeffects #syndrome ... #medications
Antidepressant Medications Decision Aid
 - The choice of depression medications in primary care is difficult as
Antidepressant Medications ... of depression medications ... across agents' toxicity ... Antidepressants #Comparison #SideEffects ... #Pharmacology #medications
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Framework Pre-Renal ... Compartment Syndrome, Medications ... Protein) • AIN: Medication ... Neurogenic Bladder (Medication ... Differential #Diagnosis #nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
algorithm Decreased renal ... potassium excretion ... • Acute renal ... failure • Chronic renal ... Diagnosis #algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Thyrotoxicosis Medications ... Renal Losses ... Non-renal losses ... Diagnosis #Algorithm #nephrology ... #low #potassium
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... with impaired renal ... function, medication ... and underlying renal
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... Fluids Shift potassium ... Sodium bicarbonate Potassium ... (if preserved renal ... #nephrology
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and
druginformation #nephrology ... #sideeffects #medications
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Metolazone) 5) Potassium-sparing ... #pharmacology #nephrology ... #medications #sites