18 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
• Myopathy (Also ... caused by hydroxychloroquine ... #MSK #Musculoskeletal ... #signs #symptoms ... #diagnosis
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
- Differential Diagnosis ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs ... #differential #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... suspected, immediate MRI ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... pulmonary TB PE ... decreased reflexes Pathophysiology ... : - MRI is modality
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... aneurysms can also ... Presentation - Systemic Symptoms ... purpura: strong sign ... , and SLE) • Urinalysis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
SLE, atherosclerotic ... purpura: Strong sign ... • Progressive symptoms ... oligoclonal bands • MRI ... tract, and often causes
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Giant A waves caused by pulmonary HTN. There are two clearly discernible descents (X and Y)
Giant A waves caused ... by pulmonary HTN ... also has Kussmaul's ... sign, causing the ... the underlying diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... • Infectious causes ... - Sjogren - Vasculitis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... mediators such as ... Pulmonary: dyspnea ... anterior/posterior MSK ... #Management #Signs