8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... HoTN, edema and effusions ... Imaging: CXR- pulmonary ... #diagnosis #management ... #hematology #oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... hepatitis • Pulmonary ... : pleural effusion ... #management #treatment ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Positive pathergy test ... is a skin prick test ... , AS Treatment: ... #management #signs ... #symptoms #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... nodules, joint effusions ... exam and imaging Treatment ... #diagnosis #management ... #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
syndrome, rheumatoid arthritis ... /Edrophonium test ... - Cogan sign ... - Peek sign 2. ... #management #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... the “Chewing gum test ... Treatment of GCA ... them, but urgent rheumatology ... #Management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... frequent attacks • Arthritis ... double contour sign ... #management #treatment ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
thickening or effusion ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... #Diagnosis #Management