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diagnosis signs erythematosus headache joint lupus management msk sle systemic disease vasculitis agglutinin algorithm ana anemia antinuclear arteritis autoantibodies autoimmune
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... or nerve root Symptoms ... #MSK #rheumatology ... #approach #workup ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... Pain - Arthritis ... noninflammatory Signs ... constitutional symptoms ... Joint #pain #Differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... , Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Behcet disease) Differential ... Nonsurgical abdominal pain ... diagnosis #management #signs ... #symptoms #rheumatology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Approach to Headaches ... - Differential ... papilledema • Horner syndrome ... ) • Systemic symptoms ... ) • Temporal arteritis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... SLE-Related Auto-Antibodies ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... #rheumatology # ... approach #workup ... #differential #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... younger pts) Differential ... chills, flank pain ... hemolytic #anemia #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Presentation - Systemic Symptoms ... purpura: strong sign ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
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