18 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically Relevant HES ... underlying hematologic disorders ... #HES #Hematology ... eosinophils #diagnosis #management ... #algorithm
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Differential Diagnosis Algorithm ... • Epinephrine Cancer ... • Metabolic disorders ... • Chronic myelogenous ... #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... adsorption onto cancer ... vonWillebrand #Syndrome ... #treatment #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... and Management ... - Immunologic disorders ... #diagnosis #hematology ... #differential #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... inflammatory disorder ... #Rheumatology # ... diagnosis #management ... #Dermatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... Autoimmunity • Chronic ... Lymphoma or other cancers ... gastric and breast cancer ... hypogammaglobulinemia #immunology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... Hepatomegaly • Skin ... lymphoproliferative disorders ... workup #oncology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Non-autoimmune rheumatologic ... with Lupus: • Chronic ... leukemia • Lung cancer ... • Cervical cancer