16 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... Crises can be precipitated ... The underlying pathophysiology ... 4 different mechanism ... of the baseline anaemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... l MD SOAP) - Risks ... changes), high MCV anemia ... patients if the cause ... #Workup #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks ... Management #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... pancytopenia Mechanisms ... and petechiae Causes ... #oncology #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... without other cause ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
reticularis Blood: Anemia ... inflammation tends to cause ... pulmonary fibrosis (mechanism ... RheumatoidArthritis #RA #pathophysiology
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
Alexia without ... the most common cause ... lobe is unable to cross ... Pathophysiology: ... neurology #diagnosis #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... prolonged rest can cause ... lying down and can cause ... Hospitalization: Mechanisms ... #pathophysiology
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
The mechanism is ... Local causes include ... Systemic causes ... include diabetes, anemia ... the nail plate caused