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hematology lupus management symptoms agammaglobulinemia auer auerrods centralretinalartery cerebritis clinical cns comparison complications crao differential disease disorders endocarditis erythematosus immunology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
She was diagnosed ... her peripheral blood ... smear showed hypogranular ... Clinical #Path #BloodSmear ... #Blood #Smear #
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 Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... smear, HIV/HCV ... test, ANA (e.g., SLE ... not required in all
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... smear or on bone ... : Blast crises ... • Peripheral smear ... Hematology #Oncology #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... should be done in ALL ... Detection of AFB by smear
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... (for secondary APS
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
GCA, SLE, GPA) - ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... is required for diagnosis ... conditions: Autoimmune (SLE ... /APLS), Malignancy ... in up to 30% of cases
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Signs of immunodeficiency ... Inability to produce all ... plasma cells in blood ... Agammaglobulinemia #XLinked #pathophysiology
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