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Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... whereby red cells clump ... individual’s red blood ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
Red cell autoagglutination ... whereby red cells clump ... individual’s red blood ... Clinical #Path #Blood ... #Smear #Microscopy
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... Clinical #Path #BloodSmear ... #Blood #Smear #
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
another peripheral blood ... smear demonstrating ... iron deficiency anemia ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Diagnosis Algorithm Blood ... Normochromic RBCs on Smear ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
This smear was from ...

Causes of spherocyte ... and hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #

Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... type ± C3d • Blood ... smear: Differential ... 2) LOOK FOR a cause
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... • Peripheral blood ... smear + DAT + further ... → Sickle Cell anemia ... Diagnosis #Algorithm #causes