153 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... PT, aPTT(liver disease ... dysplasia on the smear ... #Workup #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell disease ... #Smear #Analysis ... #hematology #microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
whereby red cells clump ... cold agglutinin disease ... individual’s red blood ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
whereby red cells clump ... cold agglutinin disease ... individual’s red blood ... Clinical #Path #Blood ... #Smear #Microscopy
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Normochromic RBCs on Smear ... Anemia of Chronic Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... Smear • Drugs ... • Liver Disease ... #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... features in most cases ... APML #Pathology #Hematology ... #Clinical #Smear
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
type ± C3d • Blood ... smear: Differential ... 2) LOOK FOR a cause ... Anemia #diagnosis #management ... #treatment #rheumatology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Tamponade Pulmonary ... Water - Pus - Blood ... Vasculature: - PE - Pulmonary ... Transverse myelitis • Hematology ... #pulmonary
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... • Nonmalignant hematologic ... : Acute blood loss ... Vasculitides, IBD, Celiac disease