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Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
whereby red cells clump ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
whereby red cells clump ... individual’s red blood ... cells (RBCs or ... Clinical #Path #Blood ... #Smear #Microscopy
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... / Normochromic RBCs ... on Smear • Chronic ... Decreased RBC ... Spherocytes on Smear
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... Smear. ... parasitemia - normocytic RBCs ... multiples per RBC ... #Smear.
Red Blood Cell Morphology Atlas

Size variation, Hemoglobin distribution,  
Hypochromia,  
Shape variation,  
Inclusions, 
Red
Red Blood Cell Morphology ... Diagnosis #Path #Blood ... #Smear #RBC #Morphology
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
on Peripheral Blood ... Smear Microscopy ... parasites per RBC ... microbiology #peripheral #blood ... #smear
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
normal peripheral blood ... smear indicates ... appearance of red blood ... the size of the RBC
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... - Peripheral Blood ... Smear ↑ abnormal ... RBCs - Reticulocyte
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
Rouleaux Flow on POCUS ... Whenever the blood ... it causes the RBCs ... to clump together ... Jugular #IJ #Vein #POCUS
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential