5 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... GH excess prior ... GH excess after ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
(GH) Growth Hormone ... excess: - ... Giantism or acromegaly ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
excess occurs before ... malignancy Pathophysiology ... islet cell tumor, excess ... Differential Diagnosis ... Diagnosis #Management #Endocrinology
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Tall Stature - Differential ... Puberty Onset • GH ... Excess • Hyperthyroidism ... Resistance • Acromegaly ... Diagnosis #Algorithm #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... bruit or signs of hormonal ... excess or hypokalaemia ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly