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A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... Clinical #Pathology #Smear ... #Microscopy #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... • Nonmalignant hematologic ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Large platelets on smear ... Large platelets on smear ... Grey Platelet Syndrome ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Peripheral Blood Smear ... Differential #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Normal Blood Smear ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... Peripheral Smear ... Peripheral blood smear ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Peripheral smear ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... IgM) • Blood smear ... hemolytic #anemia #hematology
P. falciparum ring forms on a thin smear - Dr. Christina Dean @deanchr3 #Plasmodium #falciparum #Rings #Smear #Hematology
forms on a thin smear ... falciparum #Rings #Smear ... #Hematology #Microscopy
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