12 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... the postsynaptic neuromuscular ... Ocular- 50%: Ptosis ... chewing, loss of smile ... #Gravis #diagnosis
Diagnosis of Myasthenia Gravis - Physical Exam Maneuvers
 • Sustained lateral gaze for seconds to elicit
Diagnosis of Myasthenia ... Gravis - Physical ... elicit fatigable ptosis ... • Lifting the ptotic ... #Gravis #PhysicalExam
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Sensory Changes - Differential ... Diagnosis Algorithm ... • Cardio-pulmonary ... Muscular Atrophy Neuromuscular ... Gravis • Lambert-Eaton
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Double Vision - Differential ... • Look for ptosis ... • Myasthenia ... Abnormalities Neuromuscular ... Junction • Myasthenia
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
non-localized EOM weakness ... and bilateral ptosis ... Myasthenia gravis ... #Gravis #PhysicalExam ... #clinical #video
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... Myasthenia gravis ... affecting the muscle, neuromuscular ... and weakness of ... gravis • Ocular
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #differential # ... diagnosis #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... the postsynaptic neuromuscular ... 50 years in men Diagnosis ... or respiratory weakness ... #Gravis #diagnosis
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Reverses CNS and cardiac ... In treatment of myasthenia ... gravis • Used ... Edrophonium • Used for diagnosis ... of myasthenia gravis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... disorder (Cardiac ... Postsynaptic: Myasthenia ... Gravis - Lack