8 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... the postsynaptic neuromuscular ... Ocular- 50%: Ptosis ... chewing, loss of smile ... immunologic assay - MuSK
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Cardio-pulmonary ... Muscular Atrophy Neuromuscular ... Oculomotor • Myasthenia ... Gravis • Lambert-Eaton ... Myasthenic Syndrome
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Demyelinating Disease (MS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #Weakness #Causes
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... non-localized EOM weakness ... Myasthenia gravis ... myasthenia gravis ... #Myasthenia #Gravis
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... the postsynaptic neuromuscular ... or respiratory weakness ... Symptomatic treatment Of ocular ... #Gravis #diagnosis
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Myasthenia gravis ... affecting the muscle, neuromuscular ... to ptosis and weakness ... gravis • Botulinum ... gravisOcular
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
miosis during ocular ... Reverses CNS and cardiac ... In treatment of myasthenia ... gravis • Used ... gravis • Used
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
: • Non-neuromuscular ... disorder (Cardiac ... Neuromuscular Junction ... Postsynaptic: Myasthenia ... Gravis - Lack