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diagnosis neurology differential clinical management physicalexam rheumatology video acetylcholinereceptor adverseeffects algorithm benefits dequervains diplopia endocrinology eyelid finkelstein hcq hydroxychloroquine hyperthyroidism
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... Ab to AChR blocks ... chewing, loss of smile ... Labs: - AchR antibodies ... immunologic assay - MuSK
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
Gravis (MG): • ... Corticosteroids (may cause ... of generalized AChR-MG ... because of bulbar weakness ... #MuSK #VC #NIF
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... • Cardio-pulmonary ... Oculomotor • Myasthenia ... Gravis • Lambert-Eaton ... Myasthenic Syndrome
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
non-localized EOM weakness ... Myasthenia gravis ... suspected and anti-ACh ... tumor, and always ask ... #clinical #video
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 Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Demyelinating Disease (MS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... #Gravis #diagnosis
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
QT) [very rare if ... rare with ~100 cases ... abnormalities and/or cardiac ... other diseases: myasthenia ... gravis [use with
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
irregularities • Weakness ... diffuse goiter (Graves ... Graves' disease ... Cardiac arrhythmia ... hyperthyroidism #causes
Finkelstein Test for de Quervain's Tenosynovitis The Finkelstein test is used to assess for de Quervain's tenosynovitis,
condition that causes ... , the examiner grasps ... If the patient experiences ... Tenosynovitis #clinical #video ... physicalexam #sports #msk
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