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management caudaequina sclerosis algorithm als amyotrophic bee cauda causes disorders gravis hp hypertrophic lateral ms multiple myasthenia myelitis noninflammatory pachymeningitis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
chewing, loss of smile ... life-threatening Differential ... - Peek sign ... immunologic assay - MuSK ... #neurology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... damage to sacral nerves ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Cauda Equina Syndrome ... compression of nerve ... Imaging studies: • MRI ... #syndrome #differential ... #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
spinal cord • ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... EMG) studies • MRI ... #Diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential ... and signs below ... roots -> Cauda equina ... MCTD, Sjogren syndrome ... #neurology #differential
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... resonance imaging [MRI ... (Spinal cord predominant ... #management #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
(MRI) and findings ... and/or symptoms ... and ADEM the cord ... /or optic nerve ... #differential
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
neuropathy (LHON) plus MRI ... consistent with MS ... #neurology #noninflammatory ... #differential # ... diagnosis
Hypertrophic Pachymeningitis - Differential Diagnosis Framework Pachymeningitis is a rare condition that causes areas of a layer
spinal cord and ... cause different symptoms ... brain sagging syndrome ... type 4: distal nerve ... Pachymeningitis #HP #Neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
spinal cord regions ... LMN signs in the ... fasciculations Common Symptoms ... MRI: Brain, cervical ... activity between nerve
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