6 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... Hypokalemia Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
- Differential Diagnosis ... leukemia Measure Urine ... Glucose, Acute resp. alkalosis ... Fanconi syndrome, CA ... Workup #phosphate #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... permeability Diagnosis ... prevention (statin for CVA ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... factor PRES Diagnosis ... narrowing on MRA/CTA ... #management #neurology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... and Management ... lysis) ± Urine ... Calcium 2-3g IV Ca-gluconate ... #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Hypochloremic metabolic alkalosis ... Hypocalciuria (spot urine ... Gitelman #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology