11 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... Posterior Cord Syndrome ... #Injury #Syndromes ... #diagnosis #pathophysiology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Brown-Séquard Syndrome ... Posterior Cord Syndrome ... Central Cord Syndrome ... (Ventral) Cord Syndrome
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs ... #PhysicalExam #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... of normal leg reflexes ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... #diagnosis #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Incomplete spinal cord syndromes (ISCS)
 • Central - Small Lesion - Suspended sensory deficit, classic cape
Incomplete spinal cord syndromes ... positive Romberg sign ... ISCS #Incomplete #spinalcord ... #syndromes #diagnosis ... #neurology
Neuroleptic Malignant Syndrome - Diagnosis
Neuroleptic Malignant Syndrome is an idiosyncratic reaction to antipsychotic medications classically characterized
Neuroleptic Malignant Syndrome ... Malignant Syndrome ... NMS, Serotonin Syndrome ... , Stiff-person syndrome ... #Diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... cardiomyopathy, Horner syndrome ... Miller Fisher Syndrome ... Guillain #Barre #Syndrome
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
• Symptoms and signs ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... #spinal #cord #spinalcord ... #neurology #differential
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... depressed deep tendon reflexes ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... #neurology