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differential rheumatology vasculitis algorithm eosinophils hemophagocytic hes hlh hypereosinophilia lymphohistiocytosis oncology skin activation anemia antinxp2 antinxp2dm aplastic classification clinical dermatomyositis
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... #diagnosis #hematology ... #differential #management
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... Amyloidosis • Eosinophilic ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #differential #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Criteria for Diagnosis ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
staphylococcal scalded skin syndrome ... and toxic shock syndrome ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Generalized itchy rash ... SAPHO syndrome ( ... Eosinophilic folliculitis ... #Dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... - Hepatitis, eosinophilic ... Anemia #oncology #hematology ... #diagnosis #management
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