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syndrome hematology hemophagocytic lymphohistiocytosis treatment lupus summary activation arthritis behcet capillary clarksons comparison dermatology druginduced erythematosus hemeonc leak macrophage mas
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... versus DIL • Laboratory ... : Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : HLH signs and ... Diagnosis via genetic ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... spondylitis - Sacroiliac ... (to support a diagnosis ... #workup #diagnosis ... #testing #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
pathognomonic laboratory ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... versus DIL • Laboratory ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
axial skeleton-sacroiliac ... other etiology • Laboratory ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... ▪ Autoimmune diseases ... Presentation • Common Signs ... Approach • Initial management ... #Management #Hematology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
tissues: Myalgia, paresthesia ... compartment syndrome Laboratory ... leak #syndrome #diagnosis ... #management #timeline ... #treatment #rheumatology
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