15 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Necrotizing myopathy ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... MSAs #clinical #diagnosis ... #rheumatology #
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
• Overlap Myositis ... antisynthetase syndrome ... Myopathies #IIMs #diagnosis ... #rheumatology # ... dermatology #Myopathy
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
) - MSK Radiology ... mass and NO prior signs ... - **MSK rads ... Differential diagnosis ... #msk #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
axial skeleton-sacroiliac ... • Rule out other ... #Rheumatology # ... diagnosis #management ... #Dermatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
the spinal cord (Myelopathy ... bouts of HTN Diagnostic ... • Bilateral signs ... Diagnosis: • ... #diagnosis #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Gout - Diagnosis ... sex • Metabolic syndrome ... double contour sign ... +Radiographic signs ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... urate crystals (gout ... level to exclude myositis ... #testing #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... Crystal induced (Gout ... fever • Lyme • Gout ... #MSK #rheumatology