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diagnosis nephrology algorithm potassium causes chloride management metabolic pathophysiology urine alkalosis classification defects epithelial hyperkalemia hypochloremia hypomagnesemia hypomg inherited magnesium
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
syndrome - Na-K- ... ascending limb Gitelman ... acidosis - alpha-Intercalated ... #Differential # ... Table
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... • Renal tubular ... acidosis (type ... Bartter's syndrome, Gitelman's ... #differential #
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Bartter syndrome, Gitelman ... - Metabolic acidosis ... diagnosis #Algorithm #differential ... #low
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... ↑ Aldosterone: Kidney ... Bartter syndrome, Gitelman ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... Bartter syndrome, Gitelman ... tubular acidosis ... tubular acidosis ... #differential #
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup NAGMA - Chem, ABG or VBG - Calculate Anion
(NAGMA) - Differential ... Framework and Workup ... Hypoaldosteronism - Renal Tubular ... #Diagnosis #Workup ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... alkalosis • Normal or low ... ratio 0.5%) Differential ... syndrome, Renal tubular ... acidosis (RTA))
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Transient renal tubular ... syndromes - Gitelman ... Hypomagnesemia #Differential ... #Diagnosis #Low ... #Magnesium #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... Elimination (see Table ... ) • Low K diet ... Slow - don’t delay ... Treatment #potassium #nephrology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Decreased Intake: • Low ... - Bartter - Gitelman ... unloading • Kidney ... filtration rate by tubulo-glomerular ... cause metabolic acidosis
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