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nephrology algorithm causes hypophosphatemia potassium acid anticoagulation chloride citrate disorders evaluation framework gitelman hyponatremia hypotonic management metabolic pathophysiology phosphate phosphorus
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis 1) Start with the Anion Gap (AG). 2)
Diagnosis 1) Start ... 3) Now, look at ... Differential Diagnosis ... Disorders #Evaluation #workup ... Diagnosis #acidosis
Hypokalemia Differential Algorithm Acidosis - RTA - Diarrhea pH Normal 1. Decreased Mg 2. Intracellular Shift
Hypokalemia Differential ... Algorithm Acidosis ... Algorithm #Diagnosis ... #Causes #Workup ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • Normal Acid-Base ... Metabolic acidosis ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
• Normal/low ... poisoning Normal acid-base ... the excretion of sodium ... #differential # ... diagnosis
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
- Metabolic Alkalosis ... - Metabolic acidosis ... #diagnosis #Algorithm ... #differential # ... #low
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
- Differential ... Diagnosis Framework ... Glucose, Acute resp. alkalosis ... Denosumab, Estrogen based ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... • Normal or low ... ratio 0.5%) Differential ... Renal tubular acidosis ... Gitelman #Syndrome #diagnosis
Hypophosphatemia - Differential Diagnosis Algorithm Appropriately Low Kidney Phosphate Excretion: • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Diagnosis Algorithm ... Appropriately Low ... Acute Respiratory Alkalosis ... inhibitor, Estrogen based ... #workup
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based ... Present (Uosm ≥100): Hypovolemia ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Citrate Anticoagulation Toxicity Hypernatremia (HyperNa): - Citrate solutions may have ↑ sodium content and should be paired
circulation → ↓Mg Hypocalcemia ... Anion-Gap Metabolic Acidosis ... dysfunction or low ... metabolism Metabolic alkalosis ... #diagnosis
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