14 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... c-ANCA - Vasculitis ... connective tissue disease ... (TTG) - Celiac disease ... #Associations #diseases
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Scleritis, Heart Disease ... , Rheumatoid Vasculitis ... , Pulmonary Disease ... #diagnosis #rheumatology ... #signs #symptoms
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... Nodosa (PAN), ANCA ... Diseases: IgG4- ... Related Disease ... Arthritis (RA),
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pain • Kawasaki Disease ... (Granulomatous disease ... diseases, such ... atherosclerotic disease ... most important diseases
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Secondary: CTD: SLE, RA ... • ANCA Associated ... : - Microscopic ... : • Behcet Disease ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... migrans • Lyme disease ... rheumaticum • Rheumatic ... Sarcoidosis • Crohn's disease ... gangrenosum • IBD • RA
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Parenchymal lung disease ... , Pleural disease ... , Airways disease ... and peptic ulcer disease ... Coronary artery disease
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such ... atherosclerotic disease ... most important diseases ... (GRANULOMATOUS DISEASE ... HBV Kawasaki Disease
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... - 10% SLE or RA ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... classification #rheumatology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... -> Rheumatoid Nodules ... blood vessels (vasculitis ... interstitial lung disease ... pathophysiology #signs