8 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
hepatitis Anti-CCP, Rheumatoid ... c-ANCA - Vasculitis ... Microscopic polyangiitis ... diagnosis #table #rheumatology ... #antibodies
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence microscopy ... context of other symptoms ... • Rheumatic Diseases ... ANA #patterns #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... Diagnosis: Systemic rheumatic ... Presentation - Systemic Symptoms ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cryoglobulins (Vasculitic ... Donath-Landsteiner (IgG) antibodies ... hemolytic #anemia #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic rheumatic ... Presentation: Systemic Symptoms ... • Progressive symptoms ... (PR3-ANCA)): Microscopic ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, rheumatoid arthritis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... : • Systemic rheumatic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... - Neutrophilic rheumatoid ... Leukocytoclastic vasculitis ... : - Biopsy - Microscopic ... Syndrome #diagnosis #dermatology