10 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... context of other symptoms ... • Rheumatic Diseases ... • Non-Rheumatic ... ANA #patterns #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... rheumaticum • Rheumatic ... lesions • Discoid lupus ... #dermatology #joint ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... , rheumatoid arthritis ... Arthritis: • Joint ... arthropathy • 90% joints ... : • Symptoms limited
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... Diagnosis: Systemic rheumatic ... as systemic lupus ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Elevated serum rheumatoid ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... classification #rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
- Signs and Symptoms ... vasculitis, Raynaud's ... Musculoskeletal: Joint ... Arthritis #RA #Signs #Symptoms ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... • Systemic lupus ... #Disease #Rheumatoid ... #Arthritis #laboratory
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic rheumatic ... • Progressive symptoms ... (PR3-ANCA)): Microscopic ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... - Neutrophilic rheumatoid ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... : - Biopsy - Microscopic